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People with diabetes may need special attention in any incretin-related study because changes in appetite, weight, and glucose can interact with existing medicines

Some patients using GLP-1 receptor agonists have reported mood changes, though causality remains uncertain

It has also been reported that the -glutamylcysteine synthetase is not the limiting step in plants under heavy metal stress conditions and overexpression of a bacterial glutathione synthetase gene alone in Indian mustard results in higher concentrations of glutathione in the transgenic plant 31